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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLT4, fms-related tyrosine kinase 4
Sequence ID:NM_002020
NM_182925
RefSeqGene ID:NG_011536
Entrez Gene ID:2324
Ensembl ID:ENSG00000037280

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HEMANGIOMA, CAPILLARY INFANTILE, SOMATICANTXR1
KDR
LYMPHEDEMA, HEREDITARY I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q35.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 180035054 - 180076600

 Exon Info From UCSC:
NM_002020
NM_182925

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100068206Full LengthBC167816fms-related tyrosine kinase 4
4212883IncompleteBC027302fms-related tyrosine kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002011  NP_891555  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002020 NP_002011     ig
I-set
Pkinase_Tyr
NM_182925 NP_891555 P35916 EC 2.7.10.1 ig
I-set
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U43143 AAA85215 P35916 EC 2.7.10.1
S66407 AAB28539 P35916 EC 2.7.10.1
BC167816 AAI67816    
AY233382 AAO89504 P35916 EC 2.7.10.1
AY233383 AAO89505 P35916 EC 2.7.10.1
EU826564 ACF47600 P35916 EC 2.7.10.1
EU826565 ACF47601 B5A927  
EU826566 ACF47602 B5A928  
AB209637 BAD92874 Q59F24  
AK291679 BAF84368 P35916 EC 2.7.10.1
X68203 CAA48290 P35916 EC 2.7.10.1
X69878 CAA49505 P35916 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLT4 NP_891555 M.musculus Flt4 14257 Gene Info NP_032055 87
R.norvegicus Flt4 114110   NP_446104 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta