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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TWIST1, twist homolog 1 (Drosophila)
Sequence ID:NM_000474
RefSeqGene ID:NG_008114
Entrez Gene ID:7291
Ensembl ID:ENSG00000122691

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CRANIOSYNOSTOSIS, TYPE 1 
ROBINOW-SORAUF SYNDROME 
SAETHRE-CHOTZEN SYNDROMEFGFR2

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 19154853 - 19155484

NM_000474 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
66671915509219155753
66816691915629319157294

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4125830Full LengthBC036704twist homolog 1 (Drosophila)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000474 NP_000465 Q15672 HLH

Related Sequences

 
mRNAGenPeptSwissProt
BC036704 AAH36704 Q15672
DQ896770 ABM87769  
X99268 CAA67664 Q15672

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TWIST1 NP_000465 M.musculus Twist1 22160 Gene Info NP_035788 97
R.norvegicus Twist1 85489   NP_445982 97
D.melanogaster twi 37655   NP_001033967 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta