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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TIMP3, TIMP metallopeptidase inhibitor 3
Sequence ID:NM_000362
RefSeqGene ID:NG_009117
Entrez Gene ID:7078
Ensembl ID:ENSG00000100234

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
SORSBY FUNDUS DYSTROPHY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q12.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 33257579 - 33259028

NM_000362 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
113073319680133198107
130813903324543833245520
139115023325323533253346
150316243325400333254124
162554853325516633259026

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3689386Full LengthBC014277TIMP metallopeptidase inhibitor 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000353  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000362 NP_000353 P35625 TIMP

Related Sequences

 
mRNAGenPeptSwissProt
U02571 AAA17672 P35625
L15078 AAA21815 P35625
U67195 AAB07547 P35625
S78453 AAB34532 P35625
U14394 AAB60373 P35625
BC014277 AAH14277 P35625
BT006848 AAP35494 P35625
DQ892581 ABM83507  
DQ895798 ABM86724  
D45917 BAA08348 Q6LEP5
AK314871 BAG37386 P35625
AK298126 BAG60406 B4DNZ4
X76227 CAA53813 P35625
CR456593 CAG30479 P35625
CU013193 CAK54624  
CU013481 CAK54923  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TIMP3 NP_000353 M.musculus Timp3 21859 Gene Info NP_035725 96
R.norvegicus Timp3 25358   NP_037018 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta