Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. VCL, vinculin
Sequence ID:NM_003373
RefSeqGene ID:NG_008868
Entrez Gene ID:7414
Ensembl ID:ENSG00000035403

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 75868417 - 75872103

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4520338Full LengthBC039174vinculin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003364  NP_054706  

Protein Infomation

NM_003373 NP_003364   Vinculin
NM_014000 NP_054706 P18206 Vinculin

Related Sequences

M33308 AAA61283 P18206
BC039174 AAH39174 P18206
DQ894680 ABM85606  
AK126978 BAG54414 B3KXA2
AK296509 BAG59141 B4DKC9
AK300280 BAG62039 B4DTM7
AK304823 BAG65571 B4E3Q9
BX537994 CAD97952 P18206

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens VCL NP_054706 M.musculus Vcl 22330 Gene Info NP_033528 96
R.norvegicus Vcl 305679   NP_001100718 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta