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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ACO2, aconitase 2, mitochondrial
Sequence ID:NM_001098
RefSeqGene ID:NG_032143
Entrez Gene ID:50
Ensembl ID:ENSG00000100412

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
INFANTILE CEREBELLAR-RETINAL DEGENERATION 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 41865120 - 41924655

 Exon Info From UCSC:
NM_001098

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4328775Full LengthBC014092aconitase 2, mitochondrial
5264179Full LengthBC026196aconitase 2, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001089  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001098 NP_001089 Q99798 EC 4.2.1.3 Aconitase
Aconitase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U80040 AAB38416 Q99798 EC 4.2.1.3
BC014092 AAH14092 Q99798 EC 4.2.1.3
BC026196 AAH26196 Q99798 EC 4.2.1.3
DQ893674 ABM84600    
DQ895836 ABM86762    
AK314845 BAG37362 B2RBW5  
AK293562 BAG57034 B4DEC3  
AK296260 BAG58973 B4DJW1  
AK297213 BAG59696 B4DLY4  
AK301321 BAG62870 B4DW08  
AK302691 BAG63920 B4DZ08  
CR456365 CAG30251 Q99798 EC 4.2.1.3
CR536568 CAG38805 Q99798 EC 4.2.1.3
CU012932 CAK54363    
CU013220 CAK54662    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACO2 NP_001089 M.musculus Aco2 11429 Gene Info NP_542364 97
R.norvegicus Aco2 79250   NP_077374 96
C.elegans aco-2 176121   NP_741235 76
A.gambiae AgaP_AGAP007852 1278105   XP_317642 74
D.melanogaster Acon 44149   NP_001163030 73
S.cerevisiae ACO1 851013   NP_013407 67
S.pombe SPAC24C9.06c 2541450   NP_594031 67
N.crassa NCU02366 3875941   XP_959787 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)