Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PAPPA, pregnancy-associated plasma protein A, pappalysin 1
Sequence ID:NM_002581
Entrez Gene ID:5069
Ensembl ID:ENSG00000182752

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:9q33.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 119159007 - 119160775

 Exon Info From UCSC:
NM_002581

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30340336Full LengthBC078657pregnancy-associated plasma protein A, pappalysin 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002572  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002581 NP_002572 Q13219 EC 3.4.24.79 Sushi
Peptidase_M43

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC078657 AAH78657 Q13219 EC 3.4.24.79
AY140907 AAN25598 Q8IWT8  
AY189937 AAO25648 Q86YM8  
AY302185 AAP68818 Q7Z613  
AY623010 AAV41518 Q7Z613  
AK300128 BAG61919 B4DTA7  
AK300129 BAG61920 B4DTA8  
X68280 CAA48341 Q13219 EC 3.4.24.79

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAPPA NP_002572 M.musculus Pappa 18491 Gene Info NP_067337 91
R.norvegicus Pappa 313262   NP_001101409 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)