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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MAPKAPK2, mitogen-activated protein kinase-activated protein kinase 2
Sequence ID:NM_004759
RefSeqGene ID:NG_029640
Entrez Gene ID:9261
Ensembl ID:ENSG00000162889

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 206878882 - 206906127

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5296259Full LengthBC036060mitogen-activated protein kinase-activated protein kinase 2
6267183Full LengthBC052584mitogen-activated protein kinase-activated protein kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_116584  NP_004750  

Protein Infomation

NM_004759 NP_004750     Pkinase
NM_032960 NP_116584 P49137 EC Pkinase

Related Sequences

BC036060 AAH36060 P49137 EC
BC052584 AAH52584 P49137 EC
X75346 CAA53094 P49137 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MAPKAPK2 NP_116584 R.norvegicus Mapkapk2 289014   NP_835203 96
M.musculus Mapkapk2 17164 Gene Info NP_032577 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta