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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SLC40A1, solute carrier family 40 (iron-regulated transporter), member 1
Sequence ID:NM_014585
RefSeqGene ID:NG_009027
Entrez Gene ID:30061
Ensembl ID:ENSG00000138449

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOCHROMATOSIS, TYPE 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 190426407 - 190426918

NM_014585 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
291628190425317190426916
16292270190428309190428950
22712516190430079190430324
25172643190436440190436566
26442759190437571190437686
27602919190439886190440045
29202987190444538190444605
29883381190445143190445536

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4823308Full LengthBC037733solute carrier family 40 (iron-regulated transporter), member 1
5213437Full LengthBC035893solute carrier family 40 (iron-regulated transporter), member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055400  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_014585 NP_055400 Q9NP59 FPN1

Related Sequences

 
mRNAGenPeptSwissProt
AF226614 AAF36697 Q9NP59
AF231121 AAF44330 Q9NP59
AF215636 AAF80986 Q9NP59
BC035893 AAH35893 Q9NP59
BC037733 AAH37733 Q9NP59
AF171087 AAQ13603 Q9NP59
DQ065759 AAY78556 Q4PNE6
DQ065760 AAY78557 Q4PNE6
DQ065761 AAY78558 Q4PNE6
DQ065763 AAY78560 Q4PNE3
DQ065764 AAY78561 Q4PNE2
DQ890880 ABM81806  
DQ894034 ABM84960  
AK002038 BAA92049 Q9NUS1
AK223236 BAD96956 Q53FP6
AK292146 BAF84835 A8K7Y1
AK314827 BAG37348 Q9NP59
AL136944 CAB66878 Q9NP59
CR533564 CAG38595 Q9NP59
AM393277 CAL38155  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SLC40A1 NP_055400 M.musculus Slc40a1 53945 Gene Info NP_058613 91
R.norvegicus Slc40a1 170840   NP_579849 91
A.thaliana IREG1 818427   NP_181380 35
A.thaliana IREG2 831787   NP_195977 34
N.crassa NCU08804 3878139   XP_961991 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)