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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RAB8A, RAB8A, member RAS oncogene family
Sequence ID:NM_005370
Entrez Gene ID:4218
Ensembl ID:ENSG00000167461

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, adrenal medulla, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 16222724 - 16237800

NM_005370 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
13461622248916222834
3474071622903516229095
4084681623255916232619
4695461623627916236356
5476361623824616238335
6377021623883516238900
7037531624036316240413
75421751624302116244442

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3547214Full LengthBC002977RAB8A, member RAS oncogene family

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005361  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005370 NP_005361 P61006 Ras

Related Sequences

 
mRNAGenPeptSwissProt
BC002977 AAH02977 P61006
AF498943 AAM21091 P61006
BT007184 AAP35848 P61006
DQ892523 ABM83449  
DQ895735 ABM86661  
AB209767 BAD93004 Q59EP4
AK293676 BAG57118 B4DEK7
X56741 CAA40065 P61006
CR536583 CAG38820 P61006
CR542274 CAG47070 P61006

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RAB8A NP_005361 M.musculus Rab8a 17274 Gene Info NP_075615 97
R.norvegicus Rab8a 117103   NP_446450 97
D.melanogaster Rab8 40168   NP_524172 79
C.elegans rab-8 171935   NP_491199 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta