Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PTPN6, protein tyrosine phosphatase, non-receptor type 6
Sequence ID:NM_002831
NM_080548
NM_080549
Entrez Gene ID:5777
Ensembl ID:ENSG00000111679

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 7060538 - 7070479

 Exon Info From UCSC:
NM_002831
NM_080548
NM_080549

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3138804Full LengthBC007667protein tyrosine phosphatase, non-receptor type 6
3140265Full LengthBC002523protein tyrosine phosphatase, non-receptor type 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_536858  NP_002822  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002831 NP_002822 P29350 EC 3.1.3.48 SH2
Y_phosphatase
NM_080548 NP_536858 Q53XS4   SH2
Y_phosphatase
NM_080549 NP_536859      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M74903 AAA35963 P29350 EC 3.1.3.48
M77273 AAA36610 P29350 EC 3.1.3.48
AF178946 AAD53317 P29350 EC 3.1.3.48
BC002523 AAH02523 P29350
Q53XS4
EC 3.1.3.48
BC007667 AAH07667 P29350
Q53XS4
EC 3.1.3.48
BT007390 AAP36054 Q53XS4  
DQ891946 ABM82872    
DQ895133 ABM86059    
AK223629 BAD97349 Q53EL0  
AK290421 BAF83110 P29350 EC 3.1.3.48
AK313379 BAG36177 Q53XS4  
AK298470 BAG60682 B4DPS0  
AK300167 BAG61949 B4DTD7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTPN6 NP_536858 R.norvegicus Ptpn6 116689   NP_446360 94
M.musculus Ptpn6 15170 Gene Info NP_001071173 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta