Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TIMP2, TIMP metallopeptidase inhibitor 2
Sequence ID:NM_003255
Entrez Gene ID:7077
Ensembl ID:ENSG00000035862

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 76851333 - 76918483

NM_003255 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
2029037684906276851945
290430287685360376853727
302931377686697976867087
313832387686990076870000
323936707692104076921471

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6267022Full LengthBC052605TIMP metallopeptidase inhibitor 2
30337524Full LengthBC071586TIMP metallopeptidase inhibitor 2
6055429IncompleteBC039613TIMP metallopeptidase inhibitor 2
6061436IncompleteBC040445TIMP metallopeptidase inhibitor 2
6065728IncompleteBC040039TIMP metallopeptidase inhibitor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003246  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003255 NP_003246 P16035 TIMP

Related Sequences

 
mRNAGenPeptSwissProt
M32304 AAA59581 P16035
J05593 AAA61186 P16035
S48568 AAB19474 P16035
BC052605 AAH52605 P16035
BC071586 AAH71586 P16035
HQ448393 ADQ32873  
AK294290 BAG57573 B4DFW2
X54533 CAA38400 P16035

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TIMP2 NP_003246 M.musculus Timp2 21858 Gene Info NP_035724 98
R.norvegicus Timp2 29543   NP_068824 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta