Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SIX1, SIX homeobox 1
Sequence ID:NM_005982
RefSeqGene ID:NG_008231
Entrez Gene ID:6495
Ensembl ID:ENSG00000126778

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BRACHIOOTIC SYNDROME 3 
DEAFNESS, AUTOSOMAL DOMINANT 23 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 61111988 - 61119833

NM_005982 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
218796111141761113294
188026876111534761116154

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4138234Full LengthBC008874SIX homeobox 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005973  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005982 NP_005973 Q15475 Homeobox

Related Sequences

 
mRNAGenPeptSwissProt
BC008874 AAH08874 Q15475
BT007083 AAP35746 Q15475
X91868 CAA62974 Q15475

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SIX1 NP_005973 M.musculus Six1 20471 Gene Info NP_033215 99
R.norvegicus Six1 114634   NP_446211 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)