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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MARS, methionyl-tRNA synthetase
Sequence ID:NM_004990
Entrez Gene ID:4141
Ensembl ID:ENSG00000166986

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 57881853 - 57910379

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2961615Full LengthBC002384methionyl-tRNA synthetase
4120680Full LengthBC011639methionyl-tRNA synthetase
4135154Full LengthBC011849methionyl-tRNA synthetase
4139330Full LengthBC006328methionyl-tRNA synthetase
4864644IncompleteBC015011methionyl-tRNA synthetase
5021529IncompleteBC065187methionine-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004981  

Protein Infomation

NM_004990 NP_004981 P56192 EC GST_C

Related Sequences

BC002384 AAH02384 P56192 EC
BC006328 AAH06328 P56192 EC
BC011639 AAH11639 P56192 EC
BC011849 AAH11849 P56192 EC
BC015011 AAH15011 P56192 EC
BT007338 AAP36002 P56192 EC
D84224 BAA95668 P56192 EC
AK092986 BAC04011 Q8NAB3  
AK222767 BAD96487 P56192 EC
AK290857 BAF83546 A8K492  
AK122956 BAG53819 B3KVK7  
AK293945 BAG57322 B4DF61  
AK303349 BAG64411 B4E0E9  
X94754 CAA64381 P56192 EC
Z49216 CAA89153 P56192 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MARS NP_004981 R.norvegicus Mars 299851   NP_001121131 91
M.musculus Mars 216443 Gene Info NP_001165053 90
C.elegans mrs-1 178089   NP_502196 58
D.melanogaster CG15100 37177   NP_611382 53
S.cerevisiae MES1 853181   NP_011780 52
S.pombe rar1 2540052   NP_595586 52
A.gambiae AgaP_AGAP007891 1278067   XP_317601 51
N.crassa NCU07451 3880778   XP_964638 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)