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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MCL1, myeloid cell leukemia sequence 1 (BCL2-related)
Sequence ID:NM_001197320
RefSeqGene ID:NG_029146
Entrez Gene ID:4170
Ensembl ID:ENSG00000143384

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 150548541 - 150552055

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3138465Full LengthBC017197myeloid cell leukemia sequence 1 (BCL2-related)
4770487Full LengthBC107735myeloid cell leukemia sequence 1 (BCL2-related)
6586159Full LengthBC071897myeloid cell leukemia sequence 1 (BCL2-related)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_068779  

Protein Infomation

NM_001197320 NP_001184249    
NM_021960 NP_068779 Q07820 Bcl-2
NM_182763 NP_877495    

Related Sequences

AF118124 AAD13299 Q07820
AF118276 AAF15309 Q07820
AF118277 AAF15310 Q07820
AF118278 AAF15311 Q07820
AF203373 AAG00904 Q07820
BC017197 AAH17197 Q07820
BC071897 AAH71897 Q07820
BC107735 AAI07736 Q07820
BT006640 AAP35286 Q07820
DQ893795 ABM84721  
DQ890628 ABM92245  
FJ917536 ACV83304 C8YZ26
AK312508 BAG35409 Q07820
AK294462 BAG57694 B4DG83
AK297217 BAG59700 B4DLY8
AK300499 BAG62213 B4DU51
AK304775 BAG65530 B4E3L8
AK316267 BAH14638 B4DG83

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MCL1 NP_068779 R.norvegicus Mcl1 60430   NP_068618 83
M.musculus Mcl1 17210 Gene Info NP_032588 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)