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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSK, cathepsin K
Sequence ID:NM_000396
RefSeqGene ID:NG_011848
Entrez Gene ID:1513
Ensembl ID:ENSG00000143387

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 150768709 - 150780736

NM_000396 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1688150768686150769373
689794150771643150771748
795960150772019150772184
9611179150776496150776714
11801335150778336150778491
13361458150778577150778699
14591579150779161150779281
15801702150780689150780811

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4860926Full LengthBC016058cathepsin K

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000387  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000396 NP_000387 P43235 EC 3.4.22.38 Peptidase_C1
Inhibitor_I29

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U13665 AAA65233 P43235 EC 3.4.22.38
U20280 AAA95998 P43235 EC 3.4.22.38
S79895 AAB35521 P43235 EC 3.4.22.38
BC016058 AAH16058 P43235 EC 3.4.22.38
HQ447237 ADQ31724    
CR541675 CAG46476 P43235 EC 3.4.22.38
CR541719 CAG46520 Q6FHN2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSK NP_000387 R.norvegicus Ctsk 29175   NP_113748 88
M.musculus Ctsk 13038 Gene Info NP_031828 86
A.thaliana XCP2 838677   NP_564126 45
A.thaliana XCP1 829688   NP_567983 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)