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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP11B2, cytochrome P450, family 11, subfamily B, polypeptide 2
Sequence ID:NM_000498
RefSeqGene ID:NG_008374
Entrez Gene ID:1585
Ensembl ID:ENSG00000179142

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPOALDOSTERONISM, CONGENITAL, DUE TO CMO I DEFICIENCY 
HYPOALDOSTERONISM, CONGENITAL, DUE TO CMO II DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 143991974 - 143999259

NM_000498 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11535143991974143993508
15361733143993945143994142
17341812143994222143994300
18131979143994700143994866
19802134143995679143995833
21352338143996120143996323
23392538143996461143996660
25392694143998474143998629
26952936143999017143999258

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080644BC111458cytochrome P450, family 11, subfamily B, polypeptide 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000489  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000498 NP_000489 P19099 EC 1.14.15.4
EC 1.14.15.5
p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC111458 AAI11459 P19099 EC 1.14.15.4
EC 1.14.15.5
X54741 CAA38539 P19099 EC 1.14.15.4
EC 1.14.15.5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP11B2 NP_000489 M.musculus Cyp11b1 110115 Gene Info NP_001028401 65
R.norvegicus Cyp11b1 500892   NP_036669 64
R.norvegicus Cyp11b3 353498   NP_861545 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)