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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. EXOSC4, exosome component 4
Sequence ID:NM_019037
Entrez Gene ID:54512
Ensembl ID:ENSG00000178896

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 145133528 - 145135550

NM_019037 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3613853Full LengthBC002777exosome component 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_061910  

Protein Infomation

NM_019037 NP_061910 Q9NPD3 RNase_PH

Related Sequences

AF281133 AAF82134 Q9NPD3
BC002777 AAH02777 Q9NPD3
JF432617 ADZ15834  
AK000598 BAA91279 Q9NPD3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens EXOSC4 NP_061910 R.norvegicus Exosc4 300045   NP_001128332 98
M.musculus Exosc4 109075 Gene Info NP_780608 96
D.melanogaster Ski6 34721   NP_609618 55
A.thaliana RRP41 825335   NP_191721 48
N.crassa NCU00812 3880523   XP_964355 45
C.elegans exos-4.1 178261   NP_001021274 44
S.pombe ski6 2543451   NP_594082 43
S.cerevisiae SKI6 853109   NP_011711 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)