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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ASL, argininosuccinate lyase
Sequence ID:NM_000048
NM_001024943
NM_001024944
NM_001024946
RefSeqGene ID:NG_009288
Entrez Gene ID:435
Ensembl ID:ENSG00000126522

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ARGININOSUCCINIC ACIDURIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 65540820 - 65552147

 Exon Info From UCSC:
NM_000048
NM_001024943
NM_001024944
NM_001024946

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3048146Full LengthBC008195argininosuccinate lyase
4101398Full LengthBC033146argininosuccinate lyase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001020115  NP_001020114  NP_001020117  NP_000039  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000048 NP_000039 P04424 EC 4.3.2.1 Lyase_1
NM_001024943 NP_001020114     Lyase_1
NM_001024944 NP_001020115     Lyase_1
NM_001024946 NP_001020117     Lyase_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M14218 AAA51786 P04424 EC 4.3.2.1
J03058 AAA51787 P04424 EC 4.3.2.1
M57638 AAA51788 P04424 EC 4.3.2.1
BC008195 AAH08195 P04424 EC 4.3.2.1
BC033146 AAH33146 P04424 EC 4.3.2.1
AY203938 AAP34461 Q6XYD2  
AK300519 BAG62231 B4DU69  
AK316334 BAH14705 B4DU69  
Y00753 CAA68722 P04424 EC 4.3.2.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ASL NP_000039 M.musculus Asl 109900 Gene Info NP_598529 94
R.norvegicus Asl 59085   NP_067588 90
S.pombe SPBC1539.03c 2539950   NP_596817 55
S.cerevisiae ARG4 856411   NP_011882 55
S.pombe arg7 2539980   NP_595129 55
N.crassa NCU08162 3875810   XP_959654 54
A.gambiae AgaP_AGAP008141 1277818   XP_317320 53
D.melanogaster CG9510 3771738   NP_001027234 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)