Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DDR1, discoidin domain receptor tyrosine kinase 1
Sequence ID:NM_001202521
NM_001202522
NM_001202523
NM_001954
NM_013993
NM_013994
RefSeqGene ID:NG_029066
Entrez Gene ID:780
Ensembl ID:ENSG00000204580

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 30852431 - 30867929

 Exon Info From UCSC:
NM_001954
NM_013993
NM_013994

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964574Full LengthBC008716discoidin domain receptor tyrosine kinase 1
2964574Full LengthBC013400discoidin domain receptor tyrosine kinase 1
5262509Full LengthBC070070discoidin domain receptor tyrosine kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_054699  NP_001945  NP_054700  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001202521 NP_001189450      
NM_001202522 NP_001189451      
NM_001202523 NP_001189452      
NM_001954 NP_001945     Pkinase
F5_F8_type_C
Pkinase_Tyr
NM_013993 NP_054699 Q08345 EC 2.7.10.1 F5_F8_type_C
Pkinase_Tyr
NM_013994 NP_054700     Pkinase
F5_F8_type_C
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L11315 AAA02866 Q08345 EC 2.7.10.1
L20817 AAA18019 Q08345 EC 2.7.10.1
L57508 AAB05208 Q08345 EC 2.7.10.1
BC008716 AAH08716 Q08345 EC 2.7.10.1
BC013400 AAH13400 Q08345 EC 2.7.10.1
BC070070 AAH70070 Q08345 EC 2.7.10.1
AF353182 AAK48842 Q96T62  
AF353183 AAK48843 Q96T61  
EU826613 ACF47649 Q08345 EC 2.7.10.1
EU826614 ACF47650 Q08345 EC 2.7.10.1
AK130776 BAC85426 Q6ZNR9  
AB210021 BAE06103 Q08345 EC 2.7.10.1
AK291621 BAF84310 Q08345 EC 2.7.10.1
AK294793 BAH11886 Q08345 EC 2.7.10.1
AK295643 BAH12138 B7Z3A2  
X74979 CAA52915 Q08345 EC 2.7.10.1
Z29093 CAA82335 Q08345 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DDR1 NP_054699 M.musculus Ddr1 12305 Gene Info NP_031610 94
R.norvegicus Ddr1 25678   NP_001159494 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)