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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PRKAR2A, protein kinase, cAMP-dependent, regulatory, type II, alpha
Sequence ID:NM_004157
Entrez Gene ID:5576
Ensembl ID:ENSG00000114302

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.3-p21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 48785743 - 48788669

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3629579Full LengthBC002763protein kinase, cAMP-dependent, regulatory, type II, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004148  

Protein Infomation

NM_004157 NP_004148 P13861 cNMP_binding

Related Sequences

BC002763 AAH02763 Q9BUB1
BT007225 AAP35889 Q9BUB1
AK293042 BAF85731 A8KAH7
X14968 CAA33094 P13861

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRKAR2A NP_004148 R.norvegicus Prkar2a 29699   NP_062137 90
M.musculus Prkar2a 19087 Gene Info NP_032950 89
A.gambiae AgaP_AGAP004940 1275743   XP_315029 55
D.melanogaster Pka-R2 36041   NP_523671 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta