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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GNB3, guanine nucleotide binding protein (G protein), beta polypeptide 3
Sequence ID:NM_002075
RefSeqGene ID:NG_009100
Entrez Gene ID:2784
Ensembl ID:ENSG00000111664

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERTENSIONADD1
AGT
AGTR1
AGTR1
ATP1B1
ATP1B1
CYP3A5
ECE1
NOS2
NOS3
PTGIS
RGS5
RGS5
SELE

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 6949117 - 6956558

 Exon Info From UCSC:
NM_002075

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3342882Full LengthBC002454guanine nucleotide binding protein (G protein), beta polypeptide 3
3351520Full LengthBC000115guanine nucleotide binding protein (G protein), beta polypeptide 3
4648399Full LengthBC015920guanine nucleotide binding protein (G protein), beta polypeptide 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002066  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002075 NP_002066 P16520 WD40

Related Sequences

 
mRNAGenPeptSwissProt
M31328 AAA52582 P16520
U47930 AAC50468 P16520
BC000115 AAH00115 P16520
BC002454 AAH02454 P16520
BC015920 AAH15920 Q96B71
AF501884 AAM15920 P16520
BT009800 AAP88802 P16520
DQ891959 ABM82885  
DQ895149 ABM86075  
AB209283 BAD92520 Q59G26
AB593098 BAJ84038 F1T0G4
AB593099 BAJ84039 F1T0G5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GNB3 NP_002066 M.musculus Gnb3 14695 Gene Info NP_038558 97
R.norvegicus Gnb3 60449   NP_068630 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)