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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PRKACA, protein kinase, cAMP-dependent, catalytic, alpha
Sequence ID:NM_002730
RefSeqGene ID:NG_029699
Entrez Gene ID:5566
Ensembl ID:ENSG00000072062

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 14208466 - 14224985

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6066764Full LengthBC039846protein kinase, cAMP-dependent, catalytic, alpha
6144307Full LengthBC108259protein kinase, cAMP-dependent, catalytic, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002721  

Protein Infomation

NM_002730 NP_002721 P17612 EC Pkinase
NM_207518 NP_997401      

Related Sequences

M80335 AAA60094 Q15136  
AF224718 AAF75622 P17612 EC
AF239744 AAF76426 P17612 EC
AF208004 AAG35720 P17612 EC
BC039846 AAH39846 P17612 EC
BC108259 AAI08260 P17612 EC
AK290147 BAF82836 P17612 EC
AK292284 BAF84973 A8K8B9  
X07767 CAA30597 P17612 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRKACA NP_002721 M.musculus Prkaca 18747 Gene Info NP_032880 98
R.norvegicus Prkaca 25636   NP_001094392 98
C.elegans kin-1 3565407   NP_493605 83
S.cerevisiae TPK1 853275   NP_012371 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta