Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ARHGEF1, Rho guanine nucleotide exchange factor (GEF) 1
Sequence ID:NM_004706
Entrez Gene ID:9138
Ensembl ID:ENSG00000076928

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 42399451 - 42434296

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3451036Full LengthBC034013Rho guanine nucleotide exchange factor (GEF) 1
4138058Full LengthBC011726Rho guanine nucleotide exchange factor (GEF) 1
6502165Full LengthBC067262Rho guanine nucleotide exchange factor (GEF) 1
3530329IncompleteBC005155Rho guanine nucleotide exchange factor (GEF) 1
5591331IncompleteBC064996Rho guanine nucleotide exchange factor (GEF) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004697  

Protein Infomation

NM_004706 NP_004697 Q92888 RhoGEF
NM_198977 NP_945328    
NM_199002 NP_945353    

Related Sequences

U64105 AAB17896 Q92888
BC005155 AAH05155 Q92888
BC011726 AAH11726 Q92888
BC034013 AAH34013 Q92888
BC035127 AAH35127 Q49AN3
BC067262 AAH67262 Q6NX52
BT007421 AAP36089 Q92888
DQ893592 ABM84518  
DQ895004 ABM85930  
EU832721 ACE87053  
EU832644 ACE87735  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ARHGEF1 NP_945353 R.norvegicus Arhgef1 60323   NP_067726 89
M.musculus Arhgef1 16801 Gene Info NP_001123622 88

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta