Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AKT2, v-akt murine thymoma viral oncogene homolog 2
Sequence ID:NM_001243027
NM_001243028
NM_001626
RefSeqGene ID:NG_012038
Entrez Gene ID:208
Ensembl ID:ENSG00000105221

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.1-q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 40738243 - 40743544


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40116490Full LengthBC120994v-akt murine thymoma viral oncogene homolog 2
40116493Full LengthBC120995v-akt murine thymoma viral oncogene homolog 2
3902512IncompleteBC022779v-akt murine thymoma viral oncogene homolog 2
5496641IncompleteBC032709v-akt murine thymoma viral oncogene homolog 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001617  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001243027 NP_001229956      
NM_001243028 NP_001229957      
NM_001626 NP_001617 P31751 EC 2.7.11.1 Pkinase
PH
Pkinase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M77198 AAA36585 P31751 EC 2.7.11.1
M95936 AAA58364 P31751 EC 2.7.11.1
BC022779 AAH22779 Q8TBE2  
BC032709 AAH32709 Q05BV0  
BC063421 AAH63421 Q6P4H3  
BC120994 AAI20995 P31751 EC 2.7.11.1
BC120995 AAI20996 Q0VAN0  
AK314619 BAG37185 P31751 EC 2.7.11.1
AK055779 BAG51573 B3KP61  
AK294453 BAG57690 B4DG79  
AK304209 BAH14135 B7Z8Z9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKT2 NP_001617 M.musculus Akt2 11652 Gene Info NP_031460 98
R.norvegicus Akt2 25233   NP_058789 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)