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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ARFGEF2, ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Sequence ID:NM_006420
RefSeqGene ID:NG_011490
Entrez Gene ID:10564
Ensembl ID:ENSG00000124198

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PERIVENTRICULAR HETEROTOPIA WITH MICROCEPHALY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 47607654 - 47649888

 Exon Info From UCSC:
NM_006420

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6187759IncompleteBC050449ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006411  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006420 NP_006411 Q9Y6D5 Sec7

Related Sequences

 
mRNAGenPeptSwissProt
AF084521 AAD38428 Q9Y6D5
BC050449 AAH50449 Q86TH5
AB209397 BAD92634 Q59FR3
AK022623 BAG51099 B3KMT7
AK302526 BAG63799 B4DYN7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ARFGEF2 NP_006411 M.musculus Arfgef2 99371 Gene Info NP_001078964 96
R.norvegicus Arfgef2 296380   NP_851597 95
A.thaliana AT4G35380 829691   NP_195264 38
A.thaliana AT4G38200 829976   NP_195533 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta