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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PTPN12, protein tyrosine phosphatase, non-receptor type 12
Sequence ID:NM_001131008
RefSeqGene ID:NG_008394
Entrez Gene ID:5782
Ensembl ID:ENSG00000127947

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q11.23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 77166781 - 77268981

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5268732Full LengthBC050008protein tyrosine phosphatase, non-receptor type 12

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002826  

Protein Infomation

NM_001131008 NP_001124480      
NM_001131009 NP_001124481      
NM_002835 NP_002826 Q05209 EC Y_phosphatase

Related Sequences

M93425 AAA36529 Q05209 EC
S69182 AAB30045 Q16128  
S69183 AAB30046 Q16129  
S69184 AAB30047 Q05209 EC
BC050008 AAH50008 Q05209 EC
D13380 BAA02648 Q05209 EC
AB209524 BAD92761 Q05209 EC
AK289573 BAF82262 A4D1C5  
AK296764 BAG59344 B4DKY2  
AK303602 BAG64617 B4E105  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PTPN12 NP_002826 R.norvegicus Ptpn12 117255   NP_476456 85
M.musculus Ptpn12 19248 Gene Info NP_035333 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)