Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ARHGEF25, Rho guanine nucleotide exchange factor (GEF) 25
Sequence ID:NM_133483
NM_001111270
NM_182947
NR_046223
Entrez Gene ID:115557
Ensembl ID:ENSG00000240771

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 58003962 - 58011025

 Exon Info From UCSC:
NM_001111270
NM_182947

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4179764Full LengthBC012860RhoA/RAC/CDC42 exchange factor
5311038Full LengthBC047559RhoA/RAC/CDC42 exchange factor
4213812IncompleteBC018536RhoA/RAC/CDC42 exchange factor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_891992  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001111270 NP_001104740    
NM_182947 NP_891992 Q86VW2 RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
BC012860 AAH12860 Q86VW2
BC018536 AAH18536 Q86VW2
BC047559 AAH47559 Q86VW2
AF487514 AAO49463 Q86VW2
AB370196 BAF94999 A9CQZ6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ARHGEF25 NP_001104740 R.norvegicus Arhgef25 314904   NP_955427 87
M.musculus Arhgef25 52666 Gene Info NP_082303 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)