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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ISCU, iron-sulfur cluster scaffold homolog (E. coli)
Sequence ID:NM_014301
RefSeqGene ID:NG_011857
Entrez Gene ID:23479
Ensembl ID:ENSG00000136003

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 108956395 - 108963144

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4136262Full LengthBC011906iron-sulfur cluster scaffold homolog (E. coli)
4183674Full LengthBC061903iron-sulfur cluster scaffold homolog (E. coli)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055116  NP_998760  

Protein Infomation

NM_014301 NP_055116   NifU_N
NM_213595 NP_998760 Q9H1K1 NifU_N

Related Sequences

U47101 AAC50885 Q9H1K1
AY009127 AAG37427 Q9H1K1
AY009128 AAG37428 Q9H1K1
BC011906 AAH11906 Q9H1K1
BC061903 AAH61903 Q9H1K1
DQ896294 ABM87293  
EU176420 ABW03871  
EU329002 ACA34743 B1P7G3
AK057251 BAG51892 B3KQ30
AK293202 BAG56742 B4DDI1
AK297862 BAG60191 B4DNC9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ISCU NP_998760 R.norvegicus Iscu 288740   NP_001099406 97
M.musculus Iscu 66383 Gene Info NP_079802 96
A.gambiae AgaP_AGAP005813 1276480   XP_315834 82
A.thaliana ISU1 828316   NP_193953 79
D.melanogaster CG9836 41059   NP_649840 79
A.thaliana ISU3 825719   NP_192317 74
S.cerevisiae ISU1 855968   NP_015190 72
S.cerevisiae ISU2 854401   NP_014869 72
C.elegans Y45F10D.4 178344   NP_502658 71
N.crassa NCU05778 3876185   XP_960038 70
A.thaliana ISU2 821316   NP_186751 66
S.pombe isu1 2541513   NP_592967 64
P.falciparum PF14_0518 812100   XP_001348692 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)