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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DYNC1H1, dynein, cytoplasmic 1, heavy chain 1
Sequence ID:NM_001376
RefSeqGene ID:NG_008777
Entrez Gene ID:1778
Ensembl ID:ENSG00000197102

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 20 
MENTAL RETARDATION, AUTOSOMAL DOMINANT 13 
SPINAL MUSCULAR ATROPHY, LOWER EXTREMITY, AUTOSOMAL DOMINANT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 102430992 - 102517128

 Exon Info From UCSC:
NM_001376

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3546415IncompleteBC021297dynein, cytoplasmic 1, heavy chain 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001367  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001376 NP_001367 Q14204 Dynein_heavy
AAA_5
DHC_N1
DHC_N2

Related Sequences

 
mRNAGenPeptSwissProt
L23958 AAA16065 Q14204
U53530 AAB09727 Q14204
U61737 AAC50701 Q92862
AF234785 AAF35913 Q9NRC3
BC021297 AAH21297 Q14204
BC064521 AAH64521 Q6P2H7
AB002323 BAA20783 Q14204
AB290157 BAG06711 Q14204
AK299878 BAG61728 B4DSR6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DYNC1H1 NP_001367 M.musculus Dync1h1 13424 Gene Info NP_084514 99
R.norvegicus Dync1h1 29489   NP_062099 99
A.gambiae AgaP_AGAP002015 1281103   XP_321040 73
D.melanogaster Dhc64C 38580   NP_729034 73
C.elegans dhc-1 172041   NP_491363 57
N.crassa NCU06976 3878786   XP_962616 53
P.falciparum MAL7P1.162 2654986   XP_001349194 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)