Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RUNX1, runt-related transcription factor 1
Sequence ID:NM_001001890
NM_001122607
NM_001754
RefSeqGene ID:NG_011402
Entrez Gene ID:861
Ensembl ID:ENSG00000159216

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
PICALM
SH3GL1
TERT
WHSC1L1
PLATELET DISORDER, FAMILIAL,WITH ASSOCIATED MYELOID MALIGNANCY 
RHEUMATOID ARTHRITISCD244
CIITA
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL10
NFKBIL1
PADI4
PTPN22
SLC22A4
STAT4
STAT4

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:Unknown

 Exon Info From UCSC:
NM_001001890
NM_001122607
NM_001754

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020367Full LengthBC136380runt-related transcription factor 1
9020368Full LengthBC136381runt-related transcription factor 1
9052573Full LengthBC144053runt-related transcription factor 1
5585236IncompleteBC110828runt-related transcription factor 1

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001001890 NP_001001890 Q01196 Runt
RunxI
NM_001122607 NP_001116079    
NM_001754 NP_001745   Runt
RunxI

Related Sequences

 
mRNAGenPeptSwissProt
L34598 AAA51720 Q01196
S76345 AAB33729 Q01196
S76346 AAB33730 Q01196
S76350 AAB33731 Q01196
U19601 AAB51691 Q01196
BC110828 AAI10829 Q2TAM6
BC136380 AAI36381 Q01196
BC136381 AAI36382 Q01196
BC144053 AAI44054 Q01196
D10570 BAA01426 Q01196
D43967 BAA07902 Q01196
D43968 BAA07903 Q01196
D43969 BAA07904 Q01196
D89788 BAA14020 Q01196
D89789 BAA14021 Q01196
D89790 BAA14022 Q01196
X79549 CAA56092 Q01196
X90976 CAA62464 Q01196
X90979 CAA62466 Q01196

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RUNX1 NP_001745 R.norvegicus Runx1 50662   NP_059021 96
M.musculus Runx1 12394 Gene Info NP_001104491 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)