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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSA, cathepsin A
Sequence ID:NM_000308
NM_001127695
NM_001167594
RefSeqGene ID:NG_008291
Entrez Gene ID:5476
Ensembl ID:ENSG00000064601

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GALACTOSIALIDOSIS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 44519963 - 44527456

 Exon Info From UCSC:
NM_000308
NM_001127695
NM_001167594

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3346150Full LengthBC000597cathepsin A
30348898Full LengthBC093009cathepsin A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000299  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000308 NP_000299     Peptidase_S10
NM_001127695 NP_001121167 P10619 EC 3.4.16.5  
NM_001167594 NP_001161066      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M22960 AAA36476 P10619 EC 3.4.16.5
BC000597 AAH00597 P10619 EC 3.4.16.5
BC093009 AAH93009 P10619 EC 3.4.16.5
DQ891935 ABM82861    
DQ895122 ABM86048    
AB209705 BAD92942 Q59EV6  
AK312898 BAG35745 P10619 EC 3.4.16.5
AK304536 BAG65336 B4E324  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSA NP_000299 M.musculus Ctsa 19025 Gene Info NP_032932 88
R.norvegicus Ctsa 296370   NP_001011959 85
C.elegans F13D12.6 174802   NP_496507 44
C.elegans F41C3.5 173818   NP_494846 42
A.thaliana scpl20 826903   NP_193027 41
A.thaliana scpl21 822126   NP_189169 41
S.cerevisiae YBR139W 852436   NP_009697 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)