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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IGFBP5, insulin-like growth factor binding protein 5
Sequence ID:NM_000599
Entrez Gene ID:3488
Ensembl ID:ENSG00000115461

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q33-q36Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 217541339 - 217560248

NM_000599 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4186607Full LengthBC011453insulin-like growth factor binding protein 5
4183312IncompleteBC008099insulin-like growth factor binding protein 5
4515233IncompleteBC018427insulin-like growth factor binding protein 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000590  

Protein Infomation

NM_000599 NP_000590 P24593 Thyroglobulin_1

Related Sequences

M62782 AAA53505 P24593
AF055033 AAC09368 P24593
M65062 AAD04730 P24593
BC008099 AAH08099 Q96HT5
BC011453 AAH11453 P24593
BC018427 AAH18427 Q8WV97
BT019706 AAV38512 P24593
BT019707 AAV38513 P24593
AK314992 BAG37488  
CR456809 CAG33090  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IGFBP5 NP_000590 M.musculus Igfbp5 16011 Gene Info NP_034648 95
R.norvegicus Igfbp5 25285   NP_036949 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta