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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMAD1, SMAD family member 1
Sequence ID:NM_001003688
Entrez Gene ID:4086
Ensembl ID:ENSG00000170365

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 146403962 - 146479231

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3546771Full LengthBC001878SMAD family member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005891  NP_001003688  

Protein Infomation

NM_001003688 NP_001003688 Q15797 MH1
NM_005900 NP_005891 Q15797 MH1

Related Sequences

U59423 AAB06852 Q15797
U54826 AAC50493 Q15797
U57456 AAC50621 Q15797
U59912 AAC50790 Q15797
BC001878 AAH01878 Q15797
BT007386 AAP36050 Q15797
DQ892510 ABM83436  
DQ895724 ABM86650  
AK293055 BAF85744 Q15797

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMAD1 NP_005891 M.musculus Smad1 17125 Gene Info NP_032565 99
R.norvegicus Smad1 25671   NP_037262 98
D.melanogaster Mad 33529   NP_477017 81
A.gambiae AgaP_AGAP008551 1275428   XP_314661 80

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta