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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ALDH2, aldehyde dehydrogenase 2 family (mitochondrial)
Sequence ID:NM_000690
NM_001204889
RefSeqGene ID:NG_012250
Entrez Gene ID:217
Ensembl ID:ENSG00000111275

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ALCOHOL SENSITIVITY, ACUTE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 112204751 - 112247555


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3543343Full LengthBC002967aldehyde dehydrogenase 2 family (mitochondrial)
5477768Full LengthBC071839aldehyde dehydrogenase 2 family (mitochondrial)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000681  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000690 NP_000681 P05091 EC 1.2.1.3 Aldedh
NM_001204889 NP_001191818      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M26760 AAA51694 P05091 EC 1.2.1.3
M54931 AAA62825 P05091 EC 1.2.1.3
K03001 AAB59500 P05091 EC 1.2.1.3
BC002967 AAH02967 P05091 EC 1.2.1.3
BC071839 AAH71839 P05091 EC 1.2.1.3
AY621070 AAT41621 P05091 EC 1.2.1.3
JF432260 ADZ15477    
AK223373 BAD97093 Q53FB6  
AK301375 BAG62916 B4DW54  
X05409 CAA28990 P05091 EC 1.2.1.3
Y00109 CAA68290 P05091 EC 1.2.1.3
CR456991 CAG33272 P05091 EC 1.2.1.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ALDH2 NP_000681 R.norvegicus Aldh2 29539   NP_115792 96
M.musculus Aldh2 11669 Gene Info NP_033786 96
D.melanogaster Aldh 34256   NP_609285 72
A.gambiae AgaP_AGAP003652 1274323   XP_313425 70
C.elegans alh-1 175691   NP_498081 68
C.elegans alh-2 187001   NP_503467 66
A.thaliana ALDH2B4 823955   NP_190383 63
S.cerevisiae ALD4 854556   NP_015019 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)