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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TUSC3, Tumor suppressor candidate 3
Sequence ID:NM_006765
NM_178234
RefSeqGene ID:NG_012141
Entrez Gene ID:7991
Ensembl ID:ENSG00000104723

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 7 
PROSTATE CANCERAR
BRCA2
CD82
CDH1
CHEK2
CHEK2
ELAC2
HIP1
HIP1
HNF1B
KLF6
KLF6
MAD1L1
MSR1
MXI1
MXI1
PTEN
ZFHX3

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 15601086 - 15621926

 Exon Info From UCSC:
NM_006765
NM_178234

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4334284Full LengthBC010370tumor suppressor candidate 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_839952  NP_006756  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006765 NP_006756 Q13454 OST3_OST6
NM_178234 NP_839952   OST3_OST6

Related Sequences

 
mRNAGenPeptSwissProt
U42349 AAB18374 Q13454
BC010370 AAH10370 Q13454
AY530159 AAS18677 Q6QQE4
AY562998 AAS75588 Q6Q320
AY562999 AAS75589 Q6Q319
BT020002 AAV38805 Q13454
DQ892936 ABM83862  
DQ896185 ABM87184  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TUSC3 NP_839952 M.musculus Tusc3 80286 Gene Info NP_084530 99
R.norvegicus Tusc3 290783   NP_001004212 98
A.gambiae AgaP_AGAP010010 1279437   XP_319154 61
D.melanogaster CG7830 34137   NP_609204 58
C.elegans ZK686.3 176089   NP_498691 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)