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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NDUFS1, NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Sequence ID:NM_001199981
NM_001199982
NM_001199983
NM_001199984
NM_005006
RefSeqGene ID:NG_009248
Entrez Gene ID:4719
Ensembl ID:ENSG00000023228

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MITOCHONDRIAL COMPLEX I DEFICIENCYFOXRED1
NDUFA1
NDUFA11
NDUFAF1
NDUFAF2
NDUFAF3
NDUFAF4
NDUFAF5
NDUFB3
NDUFS2
NDUFS4
NDUFS6
NDUFV1
NDUFV2
NUBPL

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q33-q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:Unknown


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4734861Full LengthBC022368NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
4819912Full LengthBC030833NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001199981 NP_001186910      
NM_001199982 NP_001186911      
NM_001199983 NP_001186912      
NM_001199984 NP_001186913      
NM_005006 NP_004997 P28331 EC 1.6.99.3
EC 1.6.5.3
Fer2
Molybdopterin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC012068 AAH12068 Q9P1A0  
BC022368 AAH22368 P28331 EC 1.6.99.3
EC 1.6.5.3
BC030833 AAH30833 P28331 EC 1.6.99.3
EC 1.6.5.3
AK295705 BAG58551 B4DIN9  
AK295966 BAG58743 B4DJ81  
AK295987 BAG58762 P28331 EC 1.6.99.3
EC 1.6.5.3
AK298320 BAG60573 P28331 EC 1.6.99.3
EC 1.6.5.3
AK300585 BAG62283 P28331 EC 1.6.99.3
EC 1.6.5.3
X61100 CAA43412 P28331 EC 1.6.99.3
EC 1.6.5.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NDUFS1 NP_001186913 R.norvegicus Ndufs1 301458   NP_001005550 95
M.musculus Ndufs1 227197 Gene Info NP_663493 94
A.gambiae AgaP_AGAP001653 1281520   XP_321442 67
D.melanogaster ND75 31762   NP_511083 63
C.elegans nuo-5 178735   NP_503733 60
N.crassa NCU01765 3873340   XP_957188 56
A.thaliana EMB1467 833729   NP_568550 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)