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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IKBKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Sequence ID:NM_001190720
Entrez Gene ID:3551
Ensembl ID:ENSG00000104365

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 42129618 - 42188494

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5784717Full LengthBC108694inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
40128020IncompleteBC127663inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
40128022IncompleteBC141978inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001547  

Protein Infomation

NM_001190720 NP_001177649      
NM_001242778 NP_001229707      
NM_001556 NP_001547 O14920 EC Pkinase

Related Sequences

AF029684 AAC51860 O14920 EC
AF031416 AAC64675 O14920 EC
AF080158 AAD08997 O14920 EC
BC006231 AAH06231 O14920 EC
BC108694 AAI08695 Q32ND9  
BC127663 AAI27664 A1L159  
BC141978 AAI41979 A1L159  
AB209090 BAD92327 Q59GL9  
AK290952 BAF83641 A8K4I7  
AK091297 BAG52329 B3KRB7  
AK298241 BAG60507 B4DP95  
AK302723 BAG63942 O14920 EC
AK303294 BAG64369 B4E0A7  
AK303528 BAG64556 O14920 EC
AK316418 BAH14789 O14920 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IKBKB NP_001547 M.musculus Ikbkb 16150 Gene Info NP_001153246 93
R.norvegicus Ikbkb 84351   NP_445807 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta