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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HIF1A, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Sequence ID:NM_001243084
RefSeqGene ID:NG_029606
Entrez Gene ID:3091
Ensembl ID:ENSG00000100644

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 62162494 - 62214971

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3842146Full LengthBC012527hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001521  

Protein Infomation

NM_001243084 NP_001230013    
NM_001530 NP_001521 Q16665 PAS_3
NM_181054 NP_851397    

Related Sequences

U22431 AAC50152 Q16665
U29165 AAC51210 Q16665
AF207601 AAF20139 Q16665
AF207602 AAF20140 Q16665
AF304431 AAG43026 Q16665
BC012527 AAH12527 Q16665
BT009776 AAP88778 Q16665
FJ790247 ACN88547 C0LZJ3
AB073325 BAB70608 Q16665
AK312397 BAG35314 B2R617
AK296876 BAG59438 B4DL76
AK299551 BAG61496 B4DS34
AK304315 BAG65167 B4E2K5
AK304436 BAG65259 B4E2U7
AB500182 BAI49183 D0VY79
AB733094 BAM28632 I7GY10

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HIF1A NP_001521 M.musculus Hif1a 15251 Gene Info NP_034561 91
R.norvegicus Hif1a 29560   NP_077335 91
D.melanogaster sima 43580   NP_524584 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta