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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. STAT5B, signal transducer and activator of transcription 5B
Sequence ID:NM_012448
RefSeqGene ID:NG_007271
Entrez Gene ID:6777
Ensembl ID:ENSG00000173757

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 40351186 - 40428403

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5553426Full LengthBC065227signal transducer and activator of transcription 5B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036580  

Protein Infomation

NM_012448 NP_036580 P51692 SH2

Related Sequences

U48730 AAC50485 P51692
U47686 AAC50491 P51692
BC020868 AAH20868 Q8WW55
BC065227 AAH65227 P51692
EU446501 ABZ92030  
AB208920 BAD92157 Q59H39

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens STAT5B NP_036580 R.norvegicus Stat5b 25126   NP_071775 97
M.musculus Stat5b 20851 Gene Info NP_035619 97
C.elegans sta-1 178465   NP_001122815 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta