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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K7, mitogen-activated protein kinase kinase kinase 7
Sequence ID:NM_003188
NM_145331
NM_145332
NM_145333
RefSeqGene ID:NG_011966
Entrez Gene ID:6885
Ensembl ID:ENSG00000135341

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 91225352 - 91296764

 Exon Info From UCSC:
NM_003188
NM_145331
NM_145332
NM_145333

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3906837Full LengthBC017715mitogen-activated protein kinase kinase kinase 7

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_663304  NP_663305  NP_663306  NP_003179  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003188 NP_003179     Pkinase
NM_145331 NP_663304 O43318 EC 2.7.11.25 Pkinase
NM_145332 NP_663305     Pkinase
NM_145333 NP_663306     Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF218074 AAF27652 O43318 EC 2.7.11.25
BC017715 AAH17715 O43318 EC 2.7.11.25
BT019654 AAV38460 Q5U0D0  
BT019655 AAV38461 Q5U0C9  
AB009356 BAA25025 O43318 EC 2.7.11.25
AB009357 BAA25026 O43318 EC 2.7.11.25
AB009358 BAA25027 O43318 EC 2.7.11.25
AK315774 BAG38124 O43318 EC 2.7.11.25
AK299268 BAG61290 B4DRH8  
AL050393 CAB43687 Q9UG54  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K7 NP_003179 M.musculus Map3k7 26409 Gene Info NP_766276 99
R.norvegicus Map3k7 313121   NP_001101390 99
D.melanogaster Tak1 39659   NP_524080 43
C.elegans Y105C5A.24 190882   NP_502888 32
C.elegans mom-4 172842   NP_492620 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta