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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. FLT1, fms-related tyrosine kinase 1
Sequence ID:NM_001159920
NM_001160030
NM_001160031
NM_002019
RefSeqGene ID:NG_012003
Entrez Gene ID:2321
Ensembl ID:ENSG00000102755

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:13q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 28877002 - 28913433

 Exon Info From UCSC:
NM_001159920
NM_001160030
NM_001160031
NM_002019

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5722772Full LengthBC039007fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002010  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001159920 NP_001153392      
NM_001160030 NP_001153502      
NM_001160031 NP_001153503      
NM_002019 NP_002010 P17948 EC 2.7.10.1 ig
I-set
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S77812 AAB34001 Q16332  
S77814 AAB34002 Q16333  
AF063657 AAC16449 P17948 EC 2.7.10.1
U01134 AAC50060 P17948 EC 2.7.10.1
BC039007 AAH39007 P17948 EC 2.7.10.1
DQ836394 ABI53803 P17948 EC 2.7.10.1
DQ836395 ABI53804 P17948 EC 2.7.10.1
DQ836396 ABI53805 P17948 EC 2.7.10.1
EF491868 ABS32268 P17948 EC 2.7.10.1
EF491869 ABS32269 P17948 EC 2.7.10.1
EF491870 ABS32270 B2BF48  
EU443152 ACA21474 B1AC84  
EU368830 ACA62948 P17948 EC 2.7.10.1
EU360600 ACB05747 P17948 EC 2.7.10.1
EU826561 ACF47597 P17948 EC 2.7.10.1
EU826562 ACF47598 B5A924  
JF509744 AFC77954 H9N1E7  
JF509745 AFC77955 H9N1E8  
AB209050 BAD92287 Q59GQ9  
AK292936 BAF85625 P17948 EC 2.7.10.1
AK300392 BAG62125 P17948 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLT1 NP_002010 R.norvegicus Flt1 54251   NP_062179 83
M.musculus Flt1 14254 Gene Info NP_034358 82
C.elegans Y50D4B.6 3565593   NP_503375 47
C.elegans W04G5.10 173049   NP_492969 45
C.elegans old-2 191738   NP_496123 43
C.elegans kin-23 173050   NP_492970 42
C.elegans old-1 191737   NP_496130 41
C.elegans kin-30 180032   NP_506771 39
C.elegans R09D1.12 174501   NP_496025 38
C.elegans kin-16 174499   NP_496017 38
C.elegans kin-15 174498   NP_741035 37
C.elegans R09D1.13 187740   NP_496022 34
C.elegans T01G5.1 180021   NP_506728 34
A.gambiae AgaP_AGAP008813 1275672   XP_314941 33
C.elegans ver-4 186632   NP_509835 33
D.melanogaster Pvr 34127   NP_001162909 32
C.elegans ver-1 175182   NP_497162 29
C.elegans ver-3 181289   NP_509836 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta