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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KPNA2, Karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Sequence ID:NM_002266
Entrez Gene ID:3838
Ensembl ID:ENSG00000182481

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q24.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 66031849 - 66042958

 Exon Info From UCSC:
NM_002266

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4105058Full LengthBC005978karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
4450470Full LengthBC053343karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
4825235Full LengthBC067848karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
9056833Full LengthBC146905karyopherin alpha 2 (RAG cohort 1, importin alpha 1)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002257  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002266 NP_002257 P52292 Arm
IBB

Related Sequences

 
mRNAGenPeptSwissProt
U09559 AAA65700 P52292
U28386 AAA69957 P52292
BC005978 AAH05978 P52292
BC053343 AAH53343 Q7Z726
BC067848 AAH67848 Q6NVW7
BC146905 AAI46906 P52292
BT006665 AAP35311 P52292
DQ893768 ABM84694  
DQ890599 ABM92216  
AK291954 BAF84643 A8K7D9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KPNA2 NP_002257 M.musculus Gm10259 100039592   XP_001473221 95
M.musculus Gm10184 100043906   XP_001481264 95
M.musculus Kpna2 16647 Gene Info NP_034785 95
R.norvegicus Kpna2 85245   NP_445935 95
R.norvegicus LOC100359600 100359600   XP_002729642 95
A.gambiae AgaP_AGAP009792 1279204   XP_318886 52
D.melanogaster Pen 34338   NP_477041 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta