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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FDFT1, farnesyl-diphosphate farnesyltransferase 1
Sequence ID:NM_004462
Entrez Gene ID:2222
Ensembl ID:ENSG00000079459

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p23.1-p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 11653081 - 11696476

NM_004462 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12511166018911660439
2523491166630211666399
3505331166717511667358
5346621167925811679386
6638541168353211683723
85510311168775211687928
103211841168902611689178
118521051169589611696816

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2961623Full LengthBC009251farnesyl-diphosphate farnesyltransferase 1
3538137Full LengthBC003573farnesyl-diphosphate farnesyltransferase 1
4514761Full LengthBC029641farnesyl-diphosphate farnesyltransferase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004453  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004462 NP_004453 Q6IAX1
P37268
EC 2.5.1.21 SQS_PSY

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L06105 AAA36645 Q6IAX1
P37268
EC 2.5.1.21
L06070 AAA60582 Q6IAX1
P37268
EC 2.5.1.21
S76822 AAB33404 P37268 EC 2.5.1.21
BC003573 AAH03573 Q6IAX1
P37268
EC 2.5.1.21
BC009251 AAH09251 P37268 EC 2.5.1.21
BC029641 AAH29641 Q6IAX1
P37268
EC 2.5.1.21
BT006704 AAP35350 Q6IAX1
P37268
EC 2.5.1.21
DQ890697 ABM81623    
DQ893882 ABM84808    
AK057726 BAG51957 B3KQ95  
AK296043 BAG58807 B4DJE5  
AK297868 BAG60195 B4DND3  
AK300059 BAG61868 B4DT56  
AK300245 BAG62012 B4DTK0  
AK301617 BAG63102 B4DWP0  
AK293545 BAH11529 B7Z1J3  
AK315993 BAH14364 B7Z1J3  
AK316033 BAH14404 B7Z9R8  
AK316182 BAH14553 B4DND3  
AK316351 BAH14722 B7Z1J3  
AK316531 BAH14902 B7Z1J3  
AK316534 BAH14905 B4DT56  
X69141 CAA48896 P37268 EC 2.5.1.21
CR457033 CAG33314 Q6IAX1
P37268
EC 2.5.1.21

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FDFT1 NP_004453 M.musculus Fdft1 14137 Gene Info NP_034321 89
R.norvegicus Fdft1 29580   NP_062111 86
S.pombe erg9 2541110   NP_595363 49
S.cerevisiae ERG9 856597   NP_012060 49
A.thaliana SQS2 829617   NP_195191 44
A.thaliana SQS1 829616   NP_195190 44
N.crassa NCU06054 3875964   XP_959817 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)