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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. CXCR4, chemokine (C-X-C motif) receptor 4
Sequence ID:NM_001008540
RefSeqGene ID:NG_011587
Entrez Gene ID:7852
Ensembl ID:ENSG00000121966

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 136872438 - 136875630

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3846345Full LengthBC020968chemokine (C-X-C motif) receptor 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001008540  NP_003458  

Protein Infomation

NM_001008540 NP_001008540   7tm_1
NM_003467 NP_003458 P61073 7tm_1

Related Sequences

L06797 AAA03209 P61073
L01639 AAA16594 P61073
M99293 AAA16617 P61073
AF025375 AAB81970 P61073
AF147204 AAF00130 P61073
BC020968 AAH20968 P61073
AF348491 AAK29630 P61073
AY242129 AAO92296 P61073
BT006660 AAP35306 P61073
AY826773 AAV97584 Q5MIL4
EU831888 ACE86647  
EU831811 ACE87329  
JF432649 ADZ15866  
D10924 BAA01722 P61073
AK312244 BAG35177 P61073
AK296674 BAG59271  
X71635 CAA50641 P61073

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CXCR4 NP_003458 M.musculus Cxcr4 12767 Gene Info NP_034041 91
R.norvegicus Cxcr4 60628   NP_071541 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta