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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TOPBP1, topoisomerase (DNA) II binding protein 1
Sequence ID:NM_007027
Entrez Gene ID:11073
Ensembl ID:ENSG00000163781

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 133319486 - 133380684

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860504Full LengthBC151237topoisomerase (DNA) II binding protein 1
8991925Full LengthBC126209topoisomerase (DNA) II binding protein 1
5395690IncompleteBC032633topoisomerase (DNA) II binding protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008958  

Protein Infomation

NM_007027 NP_008958 Q92547 BRCT

Related Sequences

BC032633 AAH32633 Q05BV8
BC126209 AAI26210 A0AV47
BC151237 AAI51238 A7E2X7
D87448 BAA13389 Q92547
AB019397 BAA34202 Q92547
AK302584 BAH13754 Q92547

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TOPBP1 NP_008958 M.musculus Topbp1 235559 Gene Info NP_795953 78
R.norvegicus Topbp1 315969   XP_236578 78

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)