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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SREBF1, sterol regulatory element binding transcription factor 1
Sequence ID:NM_001005291
RefSeqGene ID:NG_029029
Entrez Gene ID:6720
Ensembl ID:ENSG00000072310

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 17715386 - 17724178

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5264244Full LengthBC063281sterol regulatory element binding transcription factor 1
5786483Full LengthBC057388sterol regulatory element binding transcription factor 1
4650326IncompleteBC023621sterol regulatory element binding transcription factor 1
5103173IncompleteBC026962sterol regulatory element binding transcription factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004167  

Protein Infomation

NM_001005291 NP_001005291    
NM_004176 NP_004167 P36956 HLH

Related Sequences

S66167 AAB28522 P36956
S66168 AAB28523 P36956
U00968 AAC50051 P36956
BC023621 AAH23621 P36956
BC026962 AAH26962 P36956
BC057388 AAH57388 P36956
BC063281 AAH63281 P36956
AB209609 BAD92846 P36956
AB373958 BAG06742 B0I4X3
AB373959 BAG06743 B0I4X4
AK091131 BAG52289 B3KR77
AK095325 BAG53027 A8MTU8
AK128320 BAG54659 B3KXZ7
AK293795 BAG57207 B4DEU6
AK294800 BAG57920 B4DGV9
AK297113 BAG59620 B4DLQ8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SREBF1 NP_001005291 R.norvegicus Srebf1 78968   XP_213329 82
M.musculus Srebf1 20787 Gene Info NP_035610 81
A.gambiae AgaP_AGAP000076 1272195   XP_311076 39
D.melanogaster HLH106 40155   NP_524166 36
C.elegans sbp-1 176574   NP_499472 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta