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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AXIN1, axin 1
Sequence ID:NM_003502
NM_181050
RefSeqGene ID:NG_012267
Entrez Gene ID:8312
Ensembl ID:ENSG00000103126

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HEPATOBLASTOMA, SOMATICAPC
APC
CASP8
CTNNB1
MET
PDGFRL
PIK3CA
PIK3CA
TP53
TP53

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 337440 - 402399

 Exon Info From UCSC:
NM_003502
NM_181050

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5809104Full LengthBC044648axin 1
3506533IncompleteBC017447axin 1
5309734IncompleteBC035872axin 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003493  NP_851393  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003502 NP_003493 O15169 RGS
DIX
NM_181050 NP_851393   RGS
DIX

Related Sequences

 
mRNAGenPeptSwissProt
AF009674 AAC51624 O15169
BC017447 AAH17447 O15169
BC044648 AAH44648 O15169
AB208876 BAD92113 Q59H83

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AXIN1 NP_003493 R.norvegicus Axin1 79257   NP_077381 88
M.musculus Axin1 12005 Gene Info NP_033863 88
A.gambiae AgaP_AGAP002123 1281346   XP_320914 38
D.melanogaster Axn 43565   NP_733338 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta