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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PUS1, pseudouridylate synthase 1
Sequence ID:NM_001002019
RefSeqGene ID:NG_013039
Entrez Gene ID:80324
Ensembl ID:ENSG00000177192

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 132414562 - 132428404

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822709Full LengthBC009505pseudouridylate synthase 1
2822709Full LengthBC019320pseudouridylate synthase 1
3943243Full LengthBC002901pseudouridylate synthase 1
3950488IncompleteBC035964pseudouridylate synthase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001002019  NP_001002020  NP_079491  

Protein Infomation

NM_001002019 NP_001002019 Q9Y606 EC PseudoU_synth_1
NM_001002020 NP_001002020 Q9Y606 EC PseudoU_synth_1
NM_025215 NP_079491 Q9Y606 EC PseudoU_synth_1

Related Sequences

AF116238 AAD21042 Q9Y606 EC
BC002901 AAH02901 Q9Y606 EC
BC009505 AAH09505 Q9Y606 EC
BC019320 AAH19320 Q9Y606 EC
AF318369 AAL55876 Q9Y606 EC
DQ892962 ABM83888    
DQ896209 ABM87208    
AK292242 BAF84931 Q9Y606 EC
AK074659 BAG51983 Q9Y606 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PUS1 NP_079491 M.musculus Pus1 56361 Gene Info NP_062674 86
R.norvegicus Pus1 304567   NP_001020734 86
A.gambiae AgaP_AGAP002409 1273553   XP_312543 51
N.crassa NCU07528 3875209   XP_959041 47
D.melanogaster CG4159 42440   NP_001163664 46
A.thaliana AT1G76120 843944   NP_565126 44
A.thaliana AT1G20370 838625   NP_564112 43
C.elegans pus-1 180123   NP_507242 42
S.cerevisiae PUS1 855889   NP_015112 41
S.pombe pus1 2539082   NP_588446 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)