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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PREX2, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Sequence ID:NM_024870
NM_025170
Entrez Gene ID:80243
Ensembl ID:ENSG00000046889

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:8q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 68864352 - 69143897

 Exon Info From UCSC:
NM_024870
NM_025170

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100015912Full LengthBC148795phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
100015096BC146369phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_079146  NP_079446  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_024870 NP_079146 Q70Z35 PH
DEP
RhoGEF
NM_025170 NP_079446   PH
DEP
RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
BC146369 AAI46370  
BC148795 AAI48796  
AY570973 AAS59407 Q56UR8
AY508996 AAS82571 Q70Z35
AY508997 AAS82572 Q70Z35
AK023049 BAB14375 Q70Z35
AK294299 BAG57581 B4DFX0
AJ437636 CAD26885 Q70Z35
BK005160 DAA05333 Q70Z35
BK005161 DAA05334 Q70Z35

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PREX2 NP_079146 M.musculus Prex2 109294 Gene Info NP_083801 94
R.norvegicus Prex2 312912   NP_001101369 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)