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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3
Sequence ID:NM_004836
RefSeqGene ID:NG_016424
Entrez Gene ID:9451
Ensembl ID:ENSG00000172071

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
WOLCOTT-RALLISON SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 88856349 - 88926864

 Exon Info From UCSC:
NM_004836

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8992070Full LengthBC126354eukaryotic translation initiation factor 2-alpha kinase 3
8992072Full LengthBC126356eukaryotic translation initiation factor 2-alpha kinase 3

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004836 NP_004827 Q9NZJ5 EC 2.7.11.1  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF110146 AAD19961 Q9NZJ5 EC 2.7.11.1
AF193339 AAF61199 Q9NZJ5 EC 2.7.11.1
BC126354 AAI26355 Q9NZJ5 EC 2.7.11.1
BC126356 AAI26357 Q9NZJ5 EC 2.7.11.1
AK315287 BAG37696 Q9NZJ5 EC 2.7.11.1
AK128659 BAG54707 B3KY45  
CR749382 CAH18234 Q68DI6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2AK3 NP_004827 R.norvegicus Eif2ak3 29702   NP_113787 88
M.musculus Eif2ak3 13666 Gene Info NP_034251 88
D.melanogaster PEK 40653   NP_649538 39
C.elegans pek-1 181334   NP_509912 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta